A prospective study of treatments for cervical intraepithelial neoplasia and fecundability

LA Wise, SK Willis, RB Perkins, AK Wesselink… - American journal of …, 2020 - Elsevier
Background Treatments for cervical intraepithelial neoplasia remove precancerous cells
from the cervix by excising or ablating the transformation zone. Most studies show no
association between cervical intraepithelial neoplasia treatments and fertility outcomes.
However, only 2 studies have examined time to pregnancy, both using retrospective study
designs, with 1 study showing no association and the other showing a 2-fold increased risk
of infertility (time to pregnancy> 12 months) following excisional or ablative treatment …
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