A single institution experience with pediatric nasopharyngeal carcinoma: high incidence of toxicity associated with platinum-based chemotherapy plus IMRT

CU Louis, AC Paulino, S Gottschalk… - Journal of pediatric …, 2007 - journals.lww.com
… As little has been published on long-term side effects seen with combination
chemotherapy and IMRT in the treatment of pediatric patients with NPC, we are reporting
our single institution experience of 5 patients who developed significant acute and long-term
toxicities after front-line treatment with platinum-based chemotherapy plus IMRT. … survival
rates are increasing, focus must be directed at identifying the morbidities associated with
current curative therapeutic regimens and developing novel, less-toxic therapies that …
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