Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease
JC Kovacic, DWM Muller, RM Graham - Journal of molecular and cellular …, 2007 - Elsevier
Despite their names, the cytokines granulocyte-and granulocyte–macrophage-colony
stimulating factor (G-CSF and GM-CSF respectively) have actions far beyond simply
stimulating the proliferation of neutrophil and monocyte lineage cells. A comprehensive
body of evidence now exists demonstrating that G-CSF and GM-CSF effectively mobilize
bone-marrow-derived progenitor cells into the peripheral circulation. These mobilized
progenitor cells can be conveniently harvested for use in reconstituting bone marrow by …
stimulating factor (G-CSF and GM-CSF respectively) have actions far beyond simply
stimulating the proliferation of neutrophil and monocyte lineage cells. A comprehensive
body of evidence now exists demonstrating that G-CSF and GM-CSF effectively mobilize
bone-marrow-derived progenitor cells into the peripheral circulation. These mobilized
progenitor cells can be conveniently harvested for use in reconstituting bone marrow by …
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