Parkinson's disease is the second most common neurodegenerative disease, after
Alzheimer's disease, among the aging human population. The main symptoms of
Parkinson's disease such as tremor and movement disabilities are the result of degeneration
of dopaminergic neurons in substantia nigra pars compacta. The widely-accepted
subcellular factor which underlies Parkinson's disease neuropathology is the presence of
Lewy bodies with characteristic inclusions of aggregated alpha-synuclein. This small soluble …