An activatable multimodal/multifunctional nanoprobe for direct imaging of intracellular drug delivery
RN Mitra, M Doshi, X Zhang, JC Tyus, N Bengtsson… - Biomaterials, 2012 - Elsevier
Multifunctional nanoparticles integrated with imaging modalities (such as magnetic
resonance and optical) and therapeutic drugs are promising candidates for future cancer
diagnostics and therapy. While targeted drug delivery and imaging of tumor cells have been
the major focus in engineering nanoparticle probes, no extensive efforts have been made
towards developing sensing probes that can confirm and monitor intracellular drug release
events. Here, we present quantum dot (Qdot)-iron oxide (IO) based multimodal …
resonance and optical) and therapeutic drugs are promising candidates for future cancer
diagnostics and therapy. While targeted drug delivery and imaging of tumor cells have been
the major focus in engineering nanoparticle probes, no extensive efforts have been made
towards developing sensing probes that can confirm and monitor intracellular drug release
events. Here, we present quantum dot (Qdot)-iron oxide (IO) based multimodal …
