An In Vitro Phototoxicity Assay Battery (Photohaemolysis and 3T3 NRU PT test) to Assess Phototoxic Potential of Fragrances

C Nam, S An, E Lee, S Moon… - … to Laboratory Animals, 2004 - journals.sagepub.com
The purpose of this study was to compare the in vivo and in vitro phototoxicity potentials of
13 fragrances. We used the 3T3 neutral red uptake phototoxicity (3T3 NRU PT) test and the
photohaemolysis test as in vitro phototoxicity assays. In the 3T3 NRU PT test, all of the
fragrances were non-phototoxic. Six fragrances were phototoxic in the photohaemolysis test.
Three of the six photohaemolytic fragrances were phototoxic in the guinea-pig photoirritation
test. These phototoxic fragrances did not cause cellular phototoxicity, but showed a …

An in vitro phototoxicity assay battery (photohaemolysis and 3T3 NRU PT test) to assess phototoxic potential of fragrances.

NCJ Nam ChunJa, ASS An SuSun… - 2004 - cabidigitallibrary.org
The purpose of this study was to compare the in vivo and in vitro phototoxicity potentials of
13 fragrances. We used the 3T3 neutral red uptake phototoxicity (3T3 NRU PT) test and the
photohaemolysis test as in vitro phototoxicity assays. In the 3T3 NRU PT test, all of the
fragrances were non-phototoxic. Six fragrances were phototoxic in the photohaemolysis test.
Three of the six photohaemolytic fragrances were phototoxic in the guinea-pig photoirritation
test. These phototoxic fragrances did not cause cellular phototoxicity, but showed a …
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