An investigation on the polymorphisms of two DNA repair genes and susceptibility to ESCC and GCA of high-incidence region in northern China
N Wang, X Dong, R Zhou, W Guo, X Zhang… - Molecular biology reports, 2009 - Springer
Aim To investigate the possible association of three SNPs, XRCC2 C41657T, XRCC2
G4234C and XRCC3 A17893G with susceptibility to esophageal squamous cell carcinoma
(ESCC) and gastric cardia adenocarcinoma (GCA) in a population of northern China.
Methods XRCC2 C41657T, XRCC2 G4234C and XRCC3 A17893G SNP were genotyped
by polymerase-chain reaction (PCR)–restriction fragment length polymorphism (RFLP)
analysis in 583 cancer patients (329 ESCC and 254 GCA) and 614 healthy controls. Results …
G4234C and XRCC3 A17893G with susceptibility to esophageal squamous cell carcinoma
(ESCC) and gastric cardia adenocarcinoma (GCA) in a population of northern China.
Methods XRCC2 C41657T, XRCC2 G4234C and XRCC3 A17893G SNP were genotyped
by polymerase-chain reaction (PCR)–restriction fragment length polymorphism (RFLP)
analysis in 583 cancer patients (329 ESCC and 254 GCA) and 614 healthy controls. Results …
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