Aneurysmal subarachnoid hemorrhage lead to systemic upregulation of IL-23/IL-17 inflammatory axis
SR Chaudhry, E Güresir, H Vatter, TM Kinfe, D Dietrich… - Cytokine, 2017 - Elsevier
Abstract IL-23 and IL-17 are pro-inflammatory cytokines. IL-23 is secreted by activated
macrophages and dendritic cells, while IL-17 by Th17 cells. Serum IL-23 and IL-17 are
known to be elevated in numerous inflammatory diseases including neurodegenerative
diseases. The role of serum IL-23 and IL-17 in aneurysmal subarachnoid hemorrhage
(aSAH) has still not been investigated. The present work investigates the serum IL-23 and IL-
17 levels and their association with post hemorrhagic complications and clinical outcome in …
macrophages and dendritic cells, while IL-17 by Th17 cells. Serum IL-23 and IL-17 are
known to be elevated in numerous inflammatory diseases including neurodegenerative
diseases. The role of serum IL-23 and IL-17 in aneurysmal subarachnoid hemorrhage
(aSAH) has still not been investigated. The present work investigates the serum IL-23 and IL-
17 levels and their association with post hemorrhagic complications and clinical outcome in …
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