Mechanisms of cellular activation in the antiphospholipid syndrome

N Müller-Calleja, KJ Lackner - Seminars in Thrombosis and …, 2018 - thieme-connect.com
… belongs to the family of annexins that comprise a large family … ] giant phospholipid vesicles,[45]
or phospholipid suspensions … ANXA5 surface binding has been correlated with antibody

Hydroxychloroquine reduces binding of antiphospholipid antibodies to syncytiotrophoblasts and restores annexin A5 expression

XX Wu, S Guller, JH Rand - American journal of obstetrics and gynecology, 2011 - Elsevier
… of the antiphospholipid antibodies on the syncytiotrophoblasts by markedly reducing
immunoglobulin-G binding and restoring annexin A5 … that target antiphospholipid antibody

What is the mechanism (s) of antiphospholipid antibody-mediated pregnancy morbidity?

VM Abrahams, MO Borghi, PL Meroni, JH Rand… - Antiphospholipid …, 2012 - Springer
Antiphospholipid antibody binding to β2GPI can activate … –53], and these differential
observations may be a reflection of … with Annexin A5 (AnxA5) binding to membrane phospholipids. …

[图书][B] Biological Modelling Related to Molecular PET Imaging as Apoptosis

HG Keen - 2003 - search.proquest.com
antiphospholipid antibodies bind to PS, inhibiting annexin V … Anti-annexin V antibodies may
directly prevent annexin V … Vesicle membranes accommodate the molecule.There is some …

Anti-annexin V IgM and IgG autoantibodies and the risk of idiopathic recurrent spontaneous miscarriage

MS Sater, RR Finan, FE Mustafa, GM Al-Khateeb… - Journal of reproductive …, 2011 - Elsevier
anti-annexin V IgM and anti-annexin V IgG was seen in RSM cases than in control women.
We conclude that anti-annexin V IgM and IgG antibodyannexin V for phospholipid binding, …

Beyond apoptosis: the mechanism and function of phosphatidylserine asymmetry in the membrane of activating mast cells

NM Rysavy, LMN Shimoda, AM Dixon, M Speck… - …, 2014 - Taylor & Francis
… Aided by the identification of Annexin-V (AnnV) binding as a … exposure of staining were
primary antibody was omitted but all … and lipids in giant plasma membrane vesicles. Proc Natl …

The clonal analysis of anticardiolipin antibodies in a single patient with primary antiphospholipid syndrome reveals an extreme antibody heterogeneity

P Lieby, A Soley, H Levallois, B Hugel… - Blood, The Journal …, 2001 - ashpublications.org
… Other phospholipid (PL)–binding proteins such as protein C9, protein S9, and annexin V13 …
Abs were able to block up to 80% the binding of CL vesicles to IgG-bearing B cells (Figure 2F…

Task force report on “non-criteria” antiphospholipid antibody tests

…, O Amengual, T Atsumi, WL Binder… - Antiphospholipid …, 2012 - Springer
… subtypes of antibodies. … to bind phospholipids other than cardiolipin, plasma proteins, ie,
prothrombin, specific epitopes of β 2 GPI, or to interfere with the anticoagulant activity of annexin

'Non-criteria'aPL tests: report of a task force and preconference workshop at the 13th International Congress on Antiphospholipid Antibodies, Galveston, TX, USA, April …

ML Bertolaccini, O Amengual, T Atsumi, WL Binder… - Lupus, 2011 - journals.sagepub.com
… and anti-prothrombin-PS antibodies What is the role of the Annexin A5 resistance test in the
… This population of women with early pregnancy losses may be affected differently by the non-…

Current international initiatives in antiphospholipid antibody testing

R Willis, EN Harris, SS Pierangeli - Seminars in thrombosis and …, 2012 - thieme-connect.com
… functional test for resistance to annexin A5 (AnnA5) anticoagulant … reduce background/nonspecific
binding, to quantitate results … losses may be differently affected by the noncriteria aPL …