Menyanthes trifoliata L. is used in Swedish traditional medicine for the treatment of
inflammatory diseases of the kidney, eg glomerulonephritis. Earlier studies have shown that
MtL increases glomerular filtration rate after renal reperfusion ischemia. This activity was
suggested to be PAF-inhibitory since MtL also inhibited PAF-induced exocytosis in vitro on
human neutrophils (IC50= 0.16 mg/ml). The present study further characterizes the anti-
inflammatory properties of a rhizome decoction of this plant. MtL inhibited carrageenan …