[HTML][HTML] Optimal dosages and genotypes for edoxaban therapy

K Huynh - Nature Reviews Cardiology, 2015 - nature.com
… of treatment. Notably, the lower bleeding risk associated with edoxaban versus warfarin use
was … responders during the first 90 days of treatment. These results demonstrate that patients …

Pharmacogenomics of anticoagulation therapy: the last 10 years

G Ragia, VG Manolopoulos - Pharmacogenomics, 2019 - Taylor & Francis
… and most recently edoxaban have gradually dominated over … was reduced in genotype-guided
warfarin dosing arm that … , both predicting the optimal dosing of COAs and identifying …

Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: a meta-analysis

LA Linkins, PT Choi, JD Douketis - Annals of internal medicine, 2003 - acpjournals.org
… , particularly in the subgroup of patients with venous thromboembolism in whom the optimal
duration of anticoagulant therapy is unclear. These patients include those with unprovoked (…

Genotype‐guided warfarin therapy: Still of only questionable value two decades on

RR Shah - Journal of Clinical Pharmacy and Therapeutics, 2020 - Wiley Online Library
… Expectations that genotype-based warfarin dosing might … supportive of genotyping, the
effect size (benefit) is at best only … benefit with edoxaban, a novel NOAC, rather than warfarin.…

Anticoagulant therapy for women: implications for menstruation, pregnancy, and lactation

E DeLoughery, BS Bannow - Hematology, 2022 - ashpublications.org
edoxaban have both demonstrated a higher risk of uterine bleeding compared with warfarin.
… (12 hours for prophylactic dosing) to ensure neutralization of an anticoagulant effect prior to …

[HTML][HTML] Pharmacogenetic studies with oral anticoagulants. Genome-wide association studies in vitamin K antagonist and direct oral anticoagulants

N Cullell, C Carrera, E Muiño, N Torres, J Krupinski… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… whether genotype can refine maintenance dose of warfarin after some days of therapy. One
… score ≥ 3, both edoxaban doses had positive NCB compared to warfarin, in patients with …

Impact of Factor VII Polymorphism on Responsiveness to Warfarin Anticoagulant Therapy

OH Shaaban, HAE Serogy, MK Zahra… - Journal of Advances …, 2023 - archive.jibiology.com
… Patients with the FVII -401GG genotype receive significantly more warfarin on a daily …
genotype [13]. While the FVII -402 AA genotype is associated with higher daily doses of warfarin

Pharmacodynamics and pharmacokinetics of stroke therapy

M Leal Rato, MJ Diógenes, A Sebastião - Precision Medicine in Stroke, 2021 - Springer
… from the knowledge of CYP2C19 genotype, as presence of the … Optimal duration of oral
anticoagulation with dabigatran in … Edoxaban should not be given with creatine clearances under …

[图书][B] … Pulmonary Embolism Transcatheter Interventions, An Issue of Interventional Cardiology Clinics: Antiplatelet and Anticoagulation Therapy in Cardiovascular and …

LO Paz - 2024 - books.google.com
… Drs Lina Manzi and Giuseppe Gargiulo review the best … potent P2Y12 inhibitor at conventional
doses to either clopidogrel or … selection of antiplatelet therapy by means of genotyping or …

Factors affecting the safe use of oral anticoagulants

SAO Abohelaika - 2017 - theses.ncl.ac.uk
… is related to VKORC1 genotype. Based upon … warfarin therapy with the VKORC1(-1639)GG
polymorphism could have poorer anticoagulation control than those with GA or AA genotypes