Assessment of dyssynchrony by gated myocardial perfusion imaging does not improve patient management

R Lee, RV Shah, VL Murthy - Journal of Nuclear Cardiology, 2018 - Elsevier
Clinical trials have demonstrated improved outcomes with cardiac resynchronization therapy
in patients with heart failure and electrical evidence of dyssynchrony. There has been
intense effort at developing imaging markers of dyssynchrony with the aim of improved risk
stratification. However, these efforts have not been fruitful to date. This article discusses
mechanisms of cardiac dyssynchrony, reviews clinical data supporting resynchronization
therapy, and addresses the lack of convincing evidence to support the use of noninvasive …
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