Importance The risk of osteoporotic fracture with dabigatran use in patients with nonvalvular
atrial fibrillation (NVAF) is unknown. Objective To investigate the risk of osteoporotic fracture
with dabigatran vs warfarin in patients with NVAF. Design, Setting, and Participants
Retrospective cohort study using a population-wide database managed by the Hong Kong
Hospital Authority. Patients newly diagnosed with NVAF from 2010 through 2014 and
prescribed dabigatran or warfarin were matched by propensity score at a 1: 2 ratio with …

IMPORTANCE: The risk of osteoporotic fracture with dabigatran use in patients with
nonvalvular atrial fibrillation (NVAF) is unknown. OBJECTIVE: To investigate the risk of
osteoporotic fracture with dabigatran vs warfarin in patients with NVAF. DESIGN, SETTING
AND PARTICIPANTS: Retrospective cohort study using a population-wide database
managed by the Hong Kong Hospital Authority. Patients newly diagnosed with NVAF from
2010 through 2014 and prescribed dabigatran or warfarin were matched by propensity …