[HTML][HTML] Recombinant incretin-secreting microbe improves metabolic dysfunction in high-fat diet fed rodents

PM Ryan, E Patterson, RM Kent, H Stack… - Scientific reports, 2017 - nature.com
The gut hormone glucagon-like peptide (GLP)-1 and its analogues represent a new
generation of anti-diabetic drugs, which have also demonstrated propensity to modulate
host lipid metabolism. Despite this, drugs of this nature are currently limited to intramuscular
administration routes due to intestinal degradation. The aim of this study was to design a
recombinant microbial delivery vector for a GLP-1 analogue and assess the efficacy of the
therapeutic in improving host glucose, lipid and cholesterol metabolism in diet induced …

Author Correction: Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents

PM Ryan, E Patterson, RM Kent, H Stack… - Scientific …, 2020 - ncbi.nlm.nih.gov
Author Correction: Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction
in High-Fat Diet Fed Rodents - PMC … Author Correction: Recombinant Incretin-Secreting
Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents … Paul Ross
corresponding author 1, 3 …
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