Autoimmune idiopathic thrombocytopenic purpura with the subsequent occurrence of systemic lupus erythematosus.

MJ Hepburn, JC English 3rd, JH Keeling 3rd - Cutis, 1997 - europepmc.org
MJ Hepburn, JC English 3rd, JH Keeling 3rd
Cutis, 1997europepmc.org
Cutaneous manifestations of petechiae, purpura, and ecchymosis can lead the physician to
discover an underlying platelet abnormality. Autoimmune idiopathic thrombocytopenic
purpura (AITP) is a diagnosis of exclusion, mediated by a destructive IgG antibody response
to the platelets' membrane components. In addition to showing evidence of cutaneous and
mucosal bleeding (ie, epistaxis, hematuria), patients with AITP are at an increased risk for
systemic lupus erythematosus (SLE). Therefore, it is suggested that patients with AITP be …
Cutaneous manifestations of petechiae, purpura, and ecchymosis can lead the physician to discover an underlying platelet abnormality. Autoimmune idiopathic thrombocytopenic purpura (AITP) is a diagnosis of exclusion, mediated by a destructive IgG antibody response to the platelets' membrane components. In addition to showing evidence of cutaneous and mucosal bleeding (ie, epistaxis, hematuria), patients with AITP are at an increased risk for systemic lupus erythematosus (SLE). Therefore, it is suggested that patients with AITP be closely monitored for SLE.
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