Auxiliary partial orthotopic liver transplantation for acute liver failure

SP Pereira, M McCarthy, AJ Ellis, J Wendon… - Journal of …, 1997 - Elsevier
Background/Aims: Auxiliary partial orthotopic liver transplantation holds potential
advantages over conventional orthotopic liver transplantation, but experience with the
technique in acute liver failure is limited. Methods: We describe our initial experience in
seven patients (4 men, 3 women; mean age 28, range 14–35 years) with acute liver failure
(paracetamol 3, non AE 2, autoimmune 1, Ecstasy 1) who fulfilled criteria for emergency
transplantation. Preoperatively, the median international normalised ratio was seven (range …

[HTML][HTML] Auxiliary partial orthotopic liver transplantation for acute liver failure

M Shrivastav, A Rammohan… - The Annals of The …, 2019 - publishing.rcseng.ac.uk
Introduction Auxiliary partial orthotopic liver transplantation (APOLT) in acute liver failure
acts as a bridge to native liver regeneration with potential for immunosuppression free
survival. While technical concerns limit its universal acceptance, the indications in acute liver
failure also need to be examined for this procedure to ultimately succeed. Case history We
present the case of an eight-month-old girl with cryptogenic acute liver failure who
underwent APOLT. She developed postoperative liver dysfunction, most likely owing to the …
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