Bidirectional relationship of mast cells-neurovascular unit communication in neuroinflammation and its involvement in POCD
N Li, X Zhang, H Dong, Y Hu, Y Qian - Behavioural Brain Research, 2017 - Elsevier
Postoperative cognitive dysfunction (POCD) has been hypothesized to be mediated by
surgery-induced neuroinflammation, which is also a key element in the pathobiology of
neurodegenerative diseases, stroke, and neuropsychiatric disorders. There is extensive
communication between the immune system and the central nervous system (CNS).
Inflammation resulting from activation of the innate immune system cells in the periphery can
impact central nervous system behaviors, such as cognitive performance. Mast cells (MCs) …
surgery-induced neuroinflammation, which is also a key element in the pathobiology of
neurodegenerative diseases, stroke, and neuropsychiatric disorders. There is extensive
communication between the immune system and the central nervous system (CNS).
Inflammation resulting from activation of the innate immune system cells in the periphery can
impact central nervous system behaviors, such as cognitive performance. Mast cells (MCs) …
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