Biocompatibility of peritoneal dialysis fluid and influence of compositions on peritoneal fibrosis
C Higuchi, H Nishimura… - Therapeutic Apheresis and …, 2006 - Wiley Online Library
C Higuchi, H Nishimura, T Sanaka
Therapeutic Apheresis and Dialysis, 2006•Wiley Online LibraryConventional peritoneal dialysis fluid (PDF) is a bioincompatible solution because of several
components. These unphysiological compositions might contribute to the development of
peritoneal fibrosis. In the present overview we summarize the influence of each composition
of PDF (acidic pH, high concentration of glucose and glucose degradation products;
advanced glycation end‐products and lactate) on the peritoneal fibrotic changes in long
peritoneal dialysis (PD) patients. We also summarized the report of new approaches to the …
components. These unphysiological compositions might contribute to the development of
peritoneal fibrosis. In the present overview we summarize the influence of each composition
of PDF (acidic pH, high concentration of glucose and glucose degradation products;
advanced glycation end‐products and lactate) on the peritoneal fibrotic changes in long
peritoneal dialysis (PD) patients. We also summarized the report of new approaches to the …
Abstract
Conventional peritoneal dialysis fluid (PDF) is a bioincompatible solution because of several components. These unphysiological compositions might contribute to the development of peritoneal fibrosis. In the present overview we summarize the influence of each composition of PDF (acidic pH, high concentration of glucose and glucose degradation products; advanced glycation end‐products and lactate) on the peritoneal fibrotic changes in long peritoneal dialysis (PD) patients. We also summarized the report of new approaches to the prevention of peritoneal fibrosis in Japan.
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