Bioneedles™ as vaccine carriers

HJHB Hirschberg, GGP van de Wijdeven, AB Kelder… - Vaccine, 2008 - Elsevier
… Mice injected with Bioneedles with adjuvanted tetanus toxoid showed a comparable … using
the Bioneedles compared to the regular injections. We conclude that Bioneedles are good …

Bioneedles as alternative delivery system for hepatitis B vaccine

HJHB Hirschberg, GGP van de Wijdeven… - Journal of controlled …, 2010 - Elsevier
… delivery system for needle injections is the Bioneedle. Hepatitis B surface antigen (HBsAg) …
that the Bioneedle is an attractive alternative for needle injections of HBsAg vaccines. …

[HTML][HTML] Microneedle patches for vaccine delivery

H Suh, J Shin, YC Kim - Clinical and experimental vaccine …, 2014 - synapse.koreamed.org
… In addition, tetanus toxoid was used in studies for evaluating the efficacy of Bioneedle, which
are hollow implantable dissolving microneedles consisting of thermoplastic starch [40]. In …

[HTML][HTML] Syringe free vaccination with CAF01 Adjuvated Ag85B-ESAT-6 in Bioneedles provides strong and prolonged protection against tuberculosis

D Christensen, T Lindenstrøm, G van de Wijdeven… - PloS one, 2010 - journals.plos.org
vaccination we observed similar high IFN-γ levels in the Bioneedle group and the group
vaccinated … Furthermore, the protective efficacy for the two vaccination methods was comparable …

[HTML][HTML] Alternative delivery of a thermostable inactivated polio vaccine

H Kraan, I Ploemen, G van de Wijdeven, I Que, C Löwik… - Vaccine, 2015 - Elsevier
… Among the alternative delivery technologies that might be used for IPV is the Bioneedle
technology, which allows parenteral vaccine administration … Bioneedles as vaccine carriers

Microneedle systems for vaccine delivery: the story so far

MK Hossain, T Ahmed, P Bhusal… - … Review of Vaccines, 2020 - Taylor & Francis
… -mediated measles vaccine delivery with conventional vaccines using syringe and needle.
This study found that at 95% vaccine coverage, MN assisted vaccine delivery was estimated …

[HTML][HTML] Solid bioneedle-delivered influenza vaccines are highly thermostable and induce both humoral and cellular immune responses

PC Soema, GJ Willems, K van Twillert… - PloS one, 2014 - journals.plos.org
vaccine for bioneedle vaccine development. All influenza vaccine formulations delivered by
bioneedles … as the best influenza vaccine formulation for use in bioneedles, due to its ease of …

Phase 1 clinical study with Bioneedles, a delivery platform for biopharmaceuticals

GGP van de Wijdeven, HJHB Hirschberg… - European Journal of …, 2015 - Elsevier
… The final mass of a Bioneedle will then be determined by the vaccine formulation. The mass
of the Bioneedles used in this study (solid Bioneedles) is 7 … Bioneedles as vaccine carriers

[PDF][PDF] TB testing has evolved—has your practice?

QTB Gold - aohp.org
vaccines are loaded by the manufacturer into these carriers to form vaccine-prefilled-Bioneedles
(VPBs)… The loading capacity of a single Bioneedle is sufficient to hold up to 50 vaccines. …

Implications of plant glycans in the development of innovative vaccines

S Rosales-Mendoza, JA Salazar-González… - … review of vaccines, 2016 - Taylor & Francis
… opened the development of glycoconjugated vaccines that consist of a carrier protein (CP) …
and vaccine delivery vehicle; it has been used as a precursor for the production of bioneedles