Sirtuins (SIRTs) are a family of regulatory proteins of genetic information with a high degree
of conservation among species. The SIRTs are heavily involved in several physiological
functions including control of gene expression, metabolism, and aging. SIRT1 has been the
most studied sirtuin and plays important role in the prevention and progression of
neurodegenerative diseases acting in different pathways of proteins involved in brain
function. SIRT1 activation regulates important genes that also exert neuroprotective actions …