Breast cancer cells imaging by targeting methionine transporters with gadolinium-based nanoprobe
B Mehravi, MS Ardestani, M Damercheli… - Molecular imaging and …, 2014 - Springer
Purpose Early cancer diagnosis using MRI imaging is of high global interest as a non-
invasive and powerful modality. In this study, methionine was conjugated on gadolinium-
based mesoporous silica nanospheres to evaluate intra-cellular uptake and its accumulation
in human breast cancer cells. Procedures The contrast agent was synthesized and
characterized using different techniques including N 2 physisorption, thermal gravimetric
analysis, dynamic light scattering, and inductively coupled plasma atomic emission …
invasive and powerful modality. In this study, methionine was conjugated on gadolinium-
based mesoporous silica nanospheres to evaluate intra-cellular uptake and its accumulation
in human breast cancer cells. Procedures The contrast agent was synthesized and
characterized using different techniques including N 2 physisorption, thermal gravimetric
analysis, dynamic light scattering, and inductively coupled plasma atomic emission …
