C-kit receptor in the human vas deferens: distinction of mast cells, interstitial cells and interepithelial cells

R Metzger, U Rolle, HC Fiegel, FE Franke… - …, 2008 - rep.bioscientifica.com
R Metzger, U Rolle, HC Fiegel, FE Franke, K Muenstedt, H Till
Reproduction, 2008rep.bioscientifica.com
… Our findings demonstrate the presence of different c-kit receptor-positive cells also in the
human VD. Their rather ubiquitous distribution within the lamina propria and muscle layers …
The present study demonstrates the complex morphology and distribution of the c-kit
receptor (CD117) in particular cells of all layers and segments of the human VD, confirmed
by the uniform reactivity of various anti-c-kit receptor antibodies. Whereas the majority of
these cells were identified as intermingled MC, we found two distinct c-kit-positive cell types …
Abstract
The molecular mechanisms underlying the regulation of vas deferens (VD) motility and semen emission are still poorly understood.
rep.bioscientifica.com
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