[PDF][PDF] Cancer dormancy from mice to man: A review

R Marches, R Scheuermann, J Uhr - Cell Cycle, 2006 - Taylor & Francis
… In this review, we focused on our studies of cancer dormancy in a murine B cell
lymphoma and human breast cancer. Lifelong dormancy was induced in syngeneic mice by …

Persistence of microscopic human cancers in mice: alterations in the angiogenic balance accompanies loss of tumor dormancy

T Udagawa, A Fernandez, EG ACHILLES… - The FASEB …, 2002 - Wiley Online Library
… at various stages of cancer. Occult tumor cells can persist in a state of dormancy for many
years in individuals treated for cancer (2). Upon relapse, dormant cancer cells may emerge as …

Models, mechanisms and clinical evidence for cancer dormancy

JA Aguirre-Ghiso - Nature Reviews Cancer, 2007 - nature.com
… from the experimental work reviewed here, as they might offer possibilities for translating
our knowledge of cancer dormancy into the clinic. Manifestations of cancer dormancy

Controversies in clinical cancer dormancy

JW Uhr, K Pantel - Proceedings of the National Academy of …, 2011 - National Acad Sciences
… We discuss four aspects of cancer dormancy that we … dormancy early in disease to clinical
cancer dormancy, (ii) the role of both adaptive and innate immunity in controlling cancer, (iii) …

Molecular mechanisms underlying tumor dormancy

N Almog - Cancer letters, 2010 - Elsevier
… The dormant phase of tumors offers a promising therapeutic window. Cancer dormancy is a
… Indeed, although treatment of a cancer can be apparently successful, the tumor may recur …

The dormant cancer cell life cycle

TG Phan, PI Croucher - Nature Reviews Cancer, 2020 - nature.com
… In this Perspective, in accordance with Hadfield’s original definition, we use the term dormant
cancer cells to refer to non-proliferating cancer cells that have undergone G0–G1 cell cycle …

Tumor dormancy and relapse: from a natural byproduct of evolution to a disease state

MH Manjili - Cancer research, 2017 - AACR
… of the evidence of cancer dormancy, Aguirre-Ghiso suggested that cellular dormancy is an
… In Caenorhabditis elegans, pathways that sense stress will induce cellular dormancy or …

Immune-mediated dormancy: an equilibrium with cancer

MWL Teng, JB Swann, CM Koebel… - Journal of Leucocyte …, 2008 - academic.oup.com
… that immunity can indeed hold preformed cancer in check. These … cancer dormancy in
humans with the hopes of devising new, immunotherapeutic strategies to treat established cancer. …

Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch

GN Naumov, LA Akslen, J Folkman - Cell cycle, 2006 - Taylor & Francis
… In contrast, approximately 80% of poorly metastatic breast cancer cells remained as
dormant solitary cells in the mouse liver. A subset of these cells could be recovered and grown …

Tumor dormancy of primary and secondary cancers

T Udagawa - Apmis, 2008 - Wiley Online Library
… non-cancer-related deaths indicate that the majority of individuals harbor dormant cancers
that … Only a few of the microscopic cancers may progress or expand to a detectable size. Even …