[PDF][PDF] Cancer dormancy from mice to man: A review
R Marches, R Scheuermann, J Uhr - Cell Cycle, 2006 - Taylor & Francis
… In this review, we focused on our studies of cancer dormancy in a murine B cell
lymphoma and human breast cancer. Lifelong dormancy was induced in syngeneic mice by …
lymphoma and human breast cancer. Lifelong dormancy was induced in syngeneic mice by …
Persistence of microscopic human cancers in mice: alterations in the angiogenic balance accompanies loss of tumor dormancy
T Udagawa, A Fernandez, EG ACHILLES… - The FASEB …, 2002 - Wiley Online Library
… at various stages of cancer. Occult tumor cells can persist in a state of dormancy for many
years in individuals treated for cancer (2). Upon relapse, dormant cancer cells may emerge as …
years in individuals treated for cancer (2). Upon relapse, dormant cancer cells may emerge as …
Models, mechanisms and clinical evidence for cancer dormancy
JA Aguirre-Ghiso - Nature Reviews Cancer, 2007 - nature.com
… from the experimental work reviewed here, as they might offer possibilities for translating
our knowledge of cancer dormancy into the clinic. Manifestations of cancer dormancy …
our knowledge of cancer dormancy into the clinic. Manifestations of cancer dormancy …
Controversies in clinical cancer dormancy
JW Uhr, K Pantel - Proceedings of the National Academy of …, 2011 - National Acad Sciences
… We discuss four aspects of cancer dormancy that we … dormancy early in disease to clinical
cancer dormancy, (ii) the role of both adaptive and innate immunity in controlling cancer, (iii) …
cancer dormancy, (ii) the role of both adaptive and innate immunity in controlling cancer, (iii) …
Molecular mechanisms underlying tumor dormancy
N Almog - Cancer letters, 2010 - Elsevier
… The dormant phase of tumors offers a promising therapeutic window. Cancer dormancy is a
… Indeed, although treatment of a cancer can be apparently successful, the tumor may recur …
… Indeed, although treatment of a cancer can be apparently successful, the tumor may recur …
The dormant cancer cell life cycle
TG Phan, PI Croucher - Nature Reviews Cancer, 2020 - nature.com
… In this Perspective, in accordance with Hadfield’s original definition, we use the term dormant
cancer cells to refer to non-proliferating cancer cells that have undergone G0–G1 cell cycle …
cancer cells to refer to non-proliferating cancer cells that have undergone G0–G1 cell cycle …
Tumor dormancy and relapse: from a natural byproduct of evolution to a disease state
MH Manjili - Cancer research, 2017 - AACR
… of the evidence of cancer dormancy, Aguirre-Ghiso suggested that cellular dormancy is an
… In Caenorhabditis elegans, pathways that sense stress will induce cellular dormancy or …
… In Caenorhabditis elegans, pathways that sense stress will induce cellular dormancy or …
Immune-mediated dormancy: an equilibrium with cancer
MWL Teng, JB Swann, CM Koebel… - Journal of Leucocyte …, 2008 - academic.oup.com
… that immunity can indeed hold preformed cancer in check. These … cancer dormancy in
humans with the hopes of devising new, immunotherapeutic strategies to treat established cancer. …
humans with the hopes of devising new, immunotherapeutic strategies to treat established cancer. …
Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch
GN Naumov, LA Akslen, J Folkman - Cell cycle, 2006 - Taylor & Francis
… In contrast, approximately 80% of poorly metastatic breast cancer cells remained as
dormant solitary cells in the mouse liver. A subset of these cells could be recovered and grown …
dormant solitary cells in the mouse liver. A subset of these cells could be recovered and grown …
Tumor dormancy of primary and secondary cancers
T Udagawa - Apmis, 2008 - Wiley Online Library
… non-cancer-related deaths indicate that the majority of individuals harbor dormant cancers
that … Only a few of the microscopic cancers may progress or expand to a detectable size. Even …
that … Only a few of the microscopic cancers may progress or expand to a detectable size. Even …
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