Cavitation threshold of microbubbles in gel tunnels by focused ultrasound
E Sassaroli, K Hynynen - Ultrasound in medicine & biology, 2007 - Elsevier
The investigation of inertial cavitation in micro-tunnels has significant implications for the
development of therapeutic applications of ultrasound such as ultrasound-mediated drug
and gene delivery. The threshold for inertial cavitation was investigated using a passive
cavitation detector with a center frequency of 1 MHz. Micro-tunnels of various diameters (90
to 800 μm) embedded in gel were fabricated and injected with a solution of Optison™
contrast agent of concentrations 1.2% and 0.2% diluted in water. An ultrasound pulse of …
development of therapeutic applications of ultrasound such as ultrasound-mediated drug
and gene delivery. The threshold for inertial cavitation was investigated using a passive
cavitation detector with a center frequency of 1 MHz. Micro-tunnels of various diameters (90
to 800 μm) embedded in gel were fabricated and injected with a solution of Optison™
contrast agent of concentrations 1.2% and 0.2% diluted in water. An ultrasound pulse of …
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