… In this article we focus on the role that chemokines and chemokine receptors play in the
pathogenesis of multiple myeloma and the associated bone destructive process, and consider …

… Multiple myeloma (MM) is a B cell tumor characterized by its selective … the multiple myeloma
cell recruitment to the bone marrow microenvironment are not well understood. Chemokines …

… question which cytokines, chemokines, and growth factors … cytokines/chemokines in the
supernatants of 10 myeloma cell … cytokines/chemokines known to be secreted by myeloma cell …

… the expression of CXCR3 on four multiple myeloma (MM) cell … following the CXCR3/chemokine
interaction. fluorescence … Data suggest that CXCR3/chemokine loop may be important …

… of cytokines and chemokines both in … chemokine IL-8 in SMM and MM patients in an in vitro
model of human stromal cells cultured in the presence of BM supernatant derived from MGUS…

… The aim of the study was to determine the levels of selected cytokines and chemokines in
the serum of multiple myeloma (MM) patients treated with bortezomib-based regimens. A total …

… and chemokine levels, cytogenetic profiles and skeletal involvement in multiple myeloma (…
monoclonal gammopathy of uncertain significance (MGUS), smoldering MM and symptomatic …

… with multiple myeloma (MM) were found to express and secrete higher amounts of the
CXC-chemokines … receptors of each chemokine to a variable extent. When cells were exposed to …

… -tumor chemokines or blocking pro-tumor chemokines may … antibodies for pro-tumor chemokine
ligands and their receptors … -tumor chemokines, studies suggest combining chemokines …

… While multiple CCR1 antagonists have entered the drug … multiple myeloma. This review will
discuss whether current CCR1 antagonists are a viable treatment option for multiple myeloma…