Clinical remission of primary aggressive CD8+ cutaneous T-cell lymphoma after pralatrexate infusion

FA Kerdel, AR Styperek, A Maini - JAMA dermatology, 2014 - jamanetwork.com
Primary aggressive CD8+ cutaneous T-cell lymphoma (CTCL) is a rare, rapidly progressive
peripheral cutaneous malignant condition. The rapid progression is accompanied by a
dismal prognosis, despite attempts to treat with multiple treatment regiments. Herein, we
report a case of primary aggressive CD8+ CTCL that successfully responded to pralatrexate.
Report of a Case A white male patient in his 60s developed pruritic and painful plaques over
his upper body. His medical history included Wegner granulomatosis, which was …
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