Comparison of Faxitron™ versus MicroCT imaging of the skeleton of the suckling rat
N Powles-Glover, L De Schaepdrijver, J French… - Reproductive …, 2014 - Elsevier
Currently, in pre and postnatal development studies or in juvenile rat studies, bone growth is
assessed “for cause” by simple measurements of long bone length in vivo and at
termination. This manuscript compares two radiographic methods for in vivo assessment of
long bones in suckling rats; 2D imaging using a Faxitron™ and 3D imaging using μCT. This
paper illustrates that it is possible to image the unanaesthetised postnatal day 1 rat by
Faxitron™ using a simple Micropore™ tape restraint method. With isoflurane anaesthesia, it …
assessed “for cause” by simple measurements of long bone length in vivo and at
termination. This manuscript compares two radiographic methods for in vivo assessment of
long bones in suckling rats; 2D imaging using a Faxitron™ and 3D imaging using μCT. This
paper illustrates that it is possible to image the unanaesthetised postnatal day 1 rat by
Faxitron™ using a simple Micropore™ tape restraint method. With isoflurane anaesthesia, it …
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