Concurrent modulation of extracellular levels of noradrenaline and cAMP during stress and by anxiogenic-or anxiolytic-like neuropeptides in the prefrontal cortex of …

S Yoshitake, S Ijiri, J Kehr, T Yoshitake - Neurochemistry International, 2013 - Elsevier
The purpose of this study was to examine the effects of stress and the role of locally infused
anxiogenic-like neuropeptides galanin, CCK-8, vasopressin, substance P and neurokinin A,
and anxiolytic-like peptides NPY, nociceptin/orphanin FQ, somatostatin and neurotensin, on
modulation of noradrenaline (NA) and cAMP efflux monitored simultaneously by
microdialysis in the medial prefronatal cortex of awake rats. Concentrations of cAMP were
determined by a newly developed method based on derivatization of cAMP with 2 …
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