Context-dependent and invariant associations between lipids, lipoproteins, and apolipoproteins and apolipoprotein E genotype
R Frikke-Schmidt, BG Nordestgaard… - Journal of Lipid …, 2000 - ASBMB
Variation in apolipoprotein (apo) E genotypes predicts variation in plasma cholesterol and
apoB; however, the context-dependent associations between high density lipoprotein (HDL)
cholesterol, apoA-I, triglycerides, and lipoprotein [a](Lp [a]) and this polymorphism remain
unsettled. We genotyped 5,025 women and 4,035 men sampled to represent a white
general population in the age range 20 to 80+ years (mean ages 58 and 57 years for
women and men, respectively). The relative frequencies of the ε22, ε32, ε42, ε33, ε43, and …
apoB; however, the context-dependent associations between high density lipoprotein (HDL)
cholesterol, apoA-I, triglycerides, and lipoprotein [a](Lp [a]) and this polymorphism remain
unsettled. We genotyped 5,025 women and 4,035 men sampled to represent a white
general population in the age range 20 to 80+ years (mean ages 58 and 57 years for
women and men, respectively). The relative frequencies of the ε22, ε32, ε42, ε33, ε43, and …
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