Background There is little information on the cost parameters of weekly multimicronutrient supplementation programs. Objective To assess the cost parameters and cost-effectiveness of a weekly multimicronutrient supplementation program in an urban population of Peru. Methods Data from the Integrated Food Security Program (Programa Integrado de Seguridad Alimentaria PISA), which distributed capsules and foodlets to women and adolescent girls and to children under five, were extrapolated to a population of 100,000 inhabitants. Results The annual cost per community member was US 1.51.Thecost-effectivenessratiowasUS 0.12 per 1% of prevented anemia per community member. Conclusions These costs are in the upper margin of iron supplementation alone. They will decrease notably when weekly multimicronutrient supplementation programs are integrated into health packages and participation by women increases. Focusing on micronutrient deficiencies would prevent these problems, and fooddistribution programs would be effectively targeted to food-deficient populations.