Cytogenetic and molecular genetic analysis of a pediatric pleomorphic sarcoma reveals similarities to adult malignant fibrous histiocytoma
JL Palmer, S Masui, S Pritchard, DK Kalousek… - Cancer genetics and …, 1997 - Elsevier
Cytogenetic and molecular genetic studies were performed on a pleomorphic sarcoma
removed from the left atrium of a 15-year-old girl. Histologic analysis was consistent with a
storiformpleomorphic malignant fibrous histiocytoma (MFH). Although MFH is the most
common soft-tissue sarcoma of late adulthood, it is extremely rare in childhood and its
existence in the pediatric population remains controversial. Cytogenetic analysis revealed
several alterations previously associated with adult MFH, including abnormalities of …
removed from the left atrium of a 15-year-old girl. Histologic analysis was consistent with a
storiformpleomorphic malignant fibrous histiocytoma (MFH). Although MFH is the most
common soft-tissue sarcoma of late adulthood, it is extremely rare in childhood and its
existence in the pediatric population remains controversial. Cytogenetic analysis revealed
several alterations previously associated with adult MFH, including abnormalities of …
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