Δ13-Reductase dependent metabolism of prostaglandins in the mammalian brain and eye
S Basu, J Stjernschantz - Prostaglandins, leukotrienes and essential fatty …, 1997 - Elsevier
This paper describes the distribution of NAD+-dependent 15-hydroxy prostaglandin
dehydrogenase (Δ13-reductase) in the mammalian brain and eye tissues. In addition, an
NADH-dependent 15-ketoprostaglandin Δ13-reductase (15-PGDH) activity was determined
in the brain and eye tissue of some species. The rabbit brain and eye tissues were obtained
after arterial perfusion with PBS buffer while the monkey, bovine and porcine tissues were
obtained without any treatment.[3H]-PGF2α or [3H]-15-keto-17-phenyl-18, 19, 20-trinor …
dehydrogenase (Δ13-reductase) in the mammalian brain and eye tissues. In addition, an
NADH-dependent 15-ketoprostaglandin Δ13-reductase (15-PGDH) activity was determined
in the brain and eye tissue of some species. The rabbit brain and eye tissues were obtained
after arterial perfusion with PBS buffer while the monkey, bovine and porcine tissues were
obtained without any treatment.[3H]-PGF2α or [3H]-15-keto-17-phenyl-18, 19, 20-trinor …
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