Disseminated histoplasmosis mimicking laryngeal carcinoma from central India-a case report.

AM Phatak, I Bhattacharya, V Misra… - Indian Journal of …, 2006 - journals.lww.com
A 58 year old male, chronic smoker, with diabetes mellitus (Type II), residing in Madhya
Pradesh presented with dysphagia, hoarseness, odynophagia and significant weight loss.
Microlaryngoscopy showed reddish ulcerated area involving valleculae, and pharyngo-
epiglottic fold. Histopathological examination showed foamy macrophages containing
Histoplasma capsulatum. Patient initially responded to Azoles, relapsed three months after
stopping the treatment and presented with oral lesions. Biopsy showed H. capsulatum …
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