Distribution of Mayaro virus RNA in polysomes during heat shock
SLB Rosas, S Herculano, MG da Costa Carvalho - Virus research, 1997 - Elsevier
Mayaro virus (Alphavirus) infection of Aedes albopictus cells results in inhibition of cell
protein synthesis and viral proteins are preferably synthesized. When infected cells are heat
shocked, however, there is also an inhibition of viral protein synthesis, and there is
preferential synthesis of heat shock proteins. Based on these observations, the distribution
of Mayaro viral RNA in polysomes and the association of p34 (capsid protein) with ribosomal
fractions of the cells under such conditions have been analyzed. During infection, the viral …
protein synthesis and viral proteins are preferably synthesized. When infected cells are heat
shocked, however, there is also an inhibition of viral protein synthesis, and there is
preferential synthesis of heat shock proteins. Based on these observations, the distribution
of Mayaro viral RNA in polysomes and the association of p34 (capsid protein) with ribosomal
fractions of the cells under such conditions have been analyzed. During infection, the viral …
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