Does complement Factor H-Related protein 5 Nephropathy (Troodos Nephropathy) protect from rickettsial infections?
A Kousios - Medical hypotheses, 2017 - Elsevier
Abstract Complement Factor H-Related protein 5 Nephropathy (CFHR5N) is an endemic
hereditary renal disease in the island of Cyprus. Although only very recently recognized, it
has provided insight into previously unknown genetic aspects of complement-mediated
renal diseases and in fact it has contributed to the introduction of the new disease
classification,'C3 Glomerulopathy'. Herein, based on evidence from epidemiological,
genetic, clinical and basic research studies, the hypothesis that CFHR5N could be protective …
hereditary renal disease in the island of Cyprus. Although only very recently recognized, it
has provided insight into previously unknown genetic aspects of complement-mediated
renal diseases and in fact it has contributed to the introduction of the new disease
classification,'C3 Glomerulopathy'. Herein, based on evidence from epidemiological,
genetic, clinical and basic research studies, the hypothesis that CFHR5N could be protective …
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