Lymphogranuloma venereum (LGV) cases are currently re-emerging in the homosexual
community, particularly in HIV-seropositive patients. The standard treatment for this infection,
which is caused by Chlamydia trachomatis L1, L2 and L3 serotypes, is a 3-week doxycycline
regimen. The case is reported of a male patient presenting with LGV, who was rapidly cured
with moxifloxacin treatment after failure of extended treatment with cyclines. This
fluoroquinolone is known to be highly active in vitro on the LGV pathogenic agent. Thus it …

The number of Lymphogranuloma venereum (LGV) cases is currently reemerging in the
homosexual community, particularly in HIV seropositive patients. The standard treatment for
this infection caused by Chlamydia trachomatis L1, L2 and L3 serotypes is a 3 week
doxycycline regime. We report the case of a male patient presenting with an LGV and rapidly
cured by moxifloxacin after an initial clinical failure following an extended therapy with
cyclines. This fluoroquinolone is known to be highly active in vitro on the LGV pathogenic …