… that produces low peak plasma drug concentrations. Administration of dexrazoxane also …
of the drugs. Increased distribution in tumours, prolonged circulation and reduced free drug …

… drug cytotoxicity to non-tumorigenic cells and multiple cancer resistance developed in
response to drugs … , their mechanisms of action and cancer cell resistance to chemotherapy and …

… In conclusion, purine and pyrimidine antimetabolites are an important class of drugs used
in the treatment of cancer and viral diseases. Although the toxicity of these compounds can …

… to treat cancer. This review will discuss the latest ‘epi-drug’ discoveries focusing on the
chemical … and use of epigenetic modulators in pre-clinical and clinical settings against cancer. …

… targeted cancer treatment therapies. Although various targeted cancer treatment drugs can
… usually specific types of cancers for which each of the drugs will be therapeutically efficacious…

… Steroids are hormone in nature, and such hormone-like drugs are used in treatment of
cancers like lymphoma, leukemias, and multiple myeloma. Moreover, corticosteroids are …

… In cancer, the molecular processes that lead to inappropriate expression of … cancer models
and clinical trials will be outlined. HDAC inhibitors represent a new wave of anticancer drugs …

… epi-drugs sensitize multiple different cancer cells to a large variety of other treatment strategies…
estrogen receptor α (ERα) activity in breast cancer. Finally, we will discuss the potential of …

… In particular, a new class or organoarsenicals are being trialed for the treatment of …
arsenical-based compounds used in the past and present for the treatment of various forms of …

… drugs against breast and ovarian cancer and has been approved worldwide for the clinical
treatment of cancer … Hailed as having provided one of the most significant advances in cancer …