Early post-operative cognitive dysfunction after closed-loop versus manual target controlled-infusion of propofol and remifentanil in patients undergoing elective major …
G Besch, L Vettoretti, M Claveau, N Boichut, N Mahr… - Medicine, 2018 - journals.lww.com
1 Background Post-operative cognitive dysfunction (POCD) is a common complication that
has been reported to occur in 26% of patients aged 60 years or over, up to 7 days after
major non-cardiac surgery.[1] POCD is usually defined as a significant alteration of cognitive
function (especially memory and executive functions) during the postoperative period,
compared to age-and disease-matched controls.[1–3] Early POCD has been associated with
increased mortality,[4, 5] a higher rate of dementia and premature departure from the …
has been reported to occur in 26% of patients aged 60 years or over, up to 7 days after
major non-cardiac surgery.[1] POCD is usually defined as a significant alteration of cognitive
function (especially memory and executive functions) during the postoperative period,
compared to age-and disease-matched controls.[1–3] Early POCD has been associated with
increased mortality,[4, 5] a higher rate of dementia and premature departure from the …
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