Effect of acetazolamide and autoCPAP therapy on breathing disturbances among patients with obstructive sleep apnea syndrome who travel to altitude: a randomized …
TD Latshang, Y Nussbaumer-Ochsner, RM Henn… - Jama, 2012 - jamanetwork.com
Context Many patients with obstructive sleep apnea syndrome (OSA) living near sea level
travel to altitude, but this may expose them to hypoxemia and exacerbation of sleep apnea.
The treatment in this setting is not established. Objective To evaluate whether
acetazolamide and autoadjusted continuous positive airway pressure (autoCPAP) control
breathing disturbances in OSA patients at altitude. Design, Setting, and Participants
Randomized, placebo-controlled, double-blind, crossover trial involving 51 patients with …
travel to altitude, but this may expose them to hypoxemia and exacerbation of sleep apnea.
The treatment in this setting is not established. Objective To evaluate whether
acetazolamide and autoadjusted continuous positive airway pressure (autoCPAP) control
breathing disturbances in OSA patients at altitude. Design, Setting, and Participants
Randomized, placebo-controlled, double-blind, crossover trial involving 51 patients with …
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