Purpose: To determine the effectiveness of methazolamide for improving visual acuity and
macular edema in patients with retinitis pigmentosa. Methods: Seventeen subjects with
retinitis pigmentosa and chronic macular edema participated in a prospective, placebo-
controlled, double-masked, crossover design study in which either methazolamide or a
placebo was taken for 3 weeks. Visual acuity, fluorescein angiograms, and subjective
impressions were obtained at baseline and after 3 weeks of treatment with each substance …

Effect of Methazolamide on Chronic Macular Edema in Patients... : RETINA … Effect of
Methazolamide on Chronic Macular Edema in Patients with Retinitis Pigmentosa …