Effects of ATP-induced leg vasodilation on V̇o2 peak and leg O2 extraction during maximal exercise in humans

JAL Calbet, C Lundby, M Sander… - American Journal …, 2006 - journals.physiology.org
During maximal whole body exercise V̇o2 peak is limited by O2 delivery. In turn, it is
though that blood flow at near-maximal exercise must be restrained by the sympathetic
nervous system to maintain mean arterial pressure. To determine whether enhancing
vasodilation across the leg results in higher O2 delivery and leg V̇o2 during near-maximal
and maximal exercise in humans, seven men performed two maximal incremental exercise
tests on the cycle ergometer. In random order, one test was performed with and one without …
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