Effects of a new cholecystokinin analogue (JMV 236) on food intake and brain monoamines in the rat
A Gourch, M Orosco, M Rodriguez, J Martinez… - Neuropeptides, 1990 - Elsevier
JMV 236, a new cholecystokinin-octapeptide-sulfate (CCK 8 S) derivative (Boc-Tyr (SO 3)-
Nle-Gly-Trp-Nle-Asp-Phe-NH 2) has been synthesized in the Centre de Pharmacologie-
Endocrinologie (Montpellier). This peptide has been shown to present the same activity as
CCK 8 S on pancreatic amylase secretion and has the advantage of a better chemical
stability. With a view to further characterization, the effect of JMV 236 on food intake and
brain monoamine and metabolite variations was assayed in the rat after intraperitoneal (ip) …
Nle-Gly-Trp-Nle-Asp-Phe-NH 2) has been synthesized in the Centre de Pharmacologie-
Endocrinologie (Montpellier). This peptide has been shown to present the same activity as
CCK 8 S on pancreatic amylase secretion and has the advantage of a better chemical
stability. With a view to further characterization, the effect of JMV 236 on food intake and
brain monoamine and metabolite variations was assayed in the rat after intraperitoneal (ip) …
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