Inhibitory effects of idoxifene on hepatic fibrosis in rats

Y Zhou, D Yin, H Chen, J Shi, B Sha… - Acta Pharmacologica …, 2005 - nature.com
Effects of idoxifene and estradiol on NF-kappaB activation in cultured rat hepatocytes
undergoing oxidative stress. Liver … of idoxifene on cultured rat hepatocytes undergoing oxidative

[HTML][HTML] Modulation of oxidative stress by 17 β-estradiol and genistein in human hepatic cell lines in vitro

D Surico, A Ercoli, S Farruggio, G Raina… - Cellular Physiology and …, 2017 - karger.com
effects exerted by 17 β estradiol and genistein against oxidative stress in both hepatocytes
and … in LX-2, we co-cultured LX-2 with Huh7.5 supernatants for 24 h in 96-well plates. For co-…

[HTML][HTML] Beneficial and deleterious effects of female sex hormones, oral contraceptives, and phytoestrogens by immunomodulation on the liver

LE Soria-Jasso, R Cariño-Cortés… - International journal of …, 2019 - mdpi.com
… and oxidative stress, while P4 evidenced deleterious effects by … ceramide content in cultures
of primary rat hepatocytes is due … In addition, treatment with idoxifene and E2 in the hepatic …

Effects of estradiol and progesterone on tumor necrosis factor alpha-induced apoptosis in human hepatoma HuH-7 cells

X Cheng, I Shimizu, Y Yuan, M Wei, M Shen, H Huang… - Life Sciences, 2006 - Elsevier
… in rats (Lu et al., 2004), and it also inhibits ROS generation and NF-kappaB activation in
cultured rat hepatocytes in a state of prooxidant-induced oxidative stress (Inoue et al., 2003). …

Opposing effects of estradiol and progesterone on the oxidative stress-induced production of chemokine and proinflammatory cytokines in murine peritoneal …

H Huang, J He, Y Yuan, E Aoyagi… - The Journal of Medical …, 2008 - jstage.jst.go.jp
… -κB activation in cultured rat hepatocytes in a state of prooxidant-induced oxidative stress (8),
Idoxifene and estradiol enhance antiapoptotic activity through the estrogen receptor-beta in …

[HTML][HTML] Effects of estradiol and progesterone on the proinflammatory cytokine production by mononuclear cells from patients with chronic hepatitis C

Y Yuan, I Shimizu, M Shen, E Aoyagi… - World Journal of …, 2008 - ncbi.nlm.nih.gov
… receptor (ER), and that in cultured hepatocytes in a state of oxidative stress, E2 inhibited the
… -κB activation in cultured rat hepatocytes in a state of prooxidant-induced oxidative stress[6], …

[HTML][HTML] Female hepatology: favorable role of estrogen in chronic liver disease with hepatitis B virus infection

I Shimizu, N Kohno, K Tamaki, M Shono… - World Journal of …, 2007 - ncbi.nlm.nih.gov
… derived from hepatocytes undergoing oxidative stress induce … peroxidase activities in cultured
rat hepatocytes[48,49]. … review indicates that estradiol may have a beneficial effect in the …

Enhancement by estradiol 3-benzoate in thioacetamide-induced liver cirrhosis of rats

JS Kang, H Wanibuchi, K Morimura… - Toxicological …, 2005 - academic.oup.com
… the role of estrogen in liver disease, we tested the effects of estradiol-3-… Effects of idoxifene
and estradiol on NF-kappaB activation in cultured rat hepatocytes undergoing oxidative stress

Estrogen Reduces Hepatic Fibrosis

T Asaki, T Matsumoto, N Suzuki… - … Female Sex Factors …, 2012 - books.google.com
rat hepatocytes in a state of oxidative stress [5, 40]. In contrast, … Idoxifene and estradiol
enhance antiapoptotic activity … in the induction of AP-1, NF-kappaB, and glutathione S-transferase …

[HTML][HTML] Role of sex steroid receptors in pathobiology of hepatocellular carcinoma

M Kalra, J Mayes, S Assefa, AK Kaul… - World journal of …, 2008 - ncbi.nlm.nih.gov
… in cultured female rat hepatocytes[123]. Estradiol and idoxifene, two selective estrogen
Bad expression in oxidative stress-induced early apoptotic rat hepatocytes. Similar findings …