Effects of rapid increases of desflurane and sevoflurane to concentrations of 1.5 MAC on systemic vascular resistance and catecholamine response during …

G Rodig, C Keyl, M Kaluza, F Kees… - The Journal of the …, 1997 - pubs.asahq.org
Background Airway irritation was hypothesized to trigger the transient cardiovascular
stimulation associated with desflurane. The authors administered desflurane during
cardiopulmonary bypass (CPB), thus avoiding airway contact, and compared the effects of
rapid increases of desflurane to 1.5 MAC on systemic vascular resistance index (SVRI) and
catecholamine response to those of 1.5 MAC sevoflurane. Methods Forty-eight patients,
undergoing elective coronary bypass surgery, were randomly allocated to receive either …
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