Efficacy and safety of oral immunotherapy with short ragweed extract

MA Van Deusen, BL Angelini, KM Cordoro… - Annals of Allergy …, 1997 - Elsevier
BACKGROUND: Oral immunotherapy, if proven safe and effective, could be an alternative to
subcutaneous immunotherapy. OBJECTIVE: This pilot study investigated the clinic and
immunologic effects of ragweed immunotherapy using a new microencapsulated, pH-
sensitive, oral delivery system. METHODS: A double-blind, placebo-controlled trial was
conducted in 23 patients with allergic rhinitis to short ragweed. Following a baseline nasal
challenge with ragweed allergen, oral immunotherapy with encapsulated short ragweed …
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