Evaluation of the effects of chlorpyrifos combined with lipopolysaccharide stress on neuroinflammation and spatial memory in neonatal rats

P Wang, H Dai, C Zhang, J Tian, Y Deng, M Zhao… - Toxicology, 2018 - Elsevier
Chlorpyrifos (CPF) may weaken the immune defenses of children, making them vulnerable
to opportunistic bacterial infection. CPF combined with bacterial infection is a potential
problem for children during their childhood development. However, there is a lack of studies
on the joint effects of these two factors on children. Here, we assessed the effects of CPF
combined with lipopolysaccharide (LPS) on the inflammation and development of the
nervous system. In this study, the cell toxicity of CPF plus LPS in cultured astrocytes, and the …
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