Five new phenolic glycosides from Hedyotis scandens
GC Wang, T Li, FY Deng, YL Li, WC Ye - Bioorganic & medicinal chemistry …, 2013 - Elsevier
Five new phenolic glycosides, hedyotosides A–E (1–5), including a new cyanogenic
glycoside (1), along with 10 known compounds (6–15) were isolated from the whole plants
of Hedyotis scandens. The structures of compounds 1–5 were established by extensive
spectroscopic analyses and acid hydrolysis. All the isolated compounds were evaluated for
their in vitro antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect
(CPE) reduction assay. Compounds 6 and 15 showed anti-RSV effects with IC50 values of …
glycoside (1), along with 10 known compounds (6–15) were isolated from the whole plants
of Hedyotis scandens. The structures of compounds 1–5 were established by extensive
spectroscopic analyses and acid hydrolysis. All the isolated compounds were evaluated for
their in vitro antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect
(CPE) reduction assay. Compounds 6 and 15 showed anti-RSV effects with IC50 values of …
Five new phenolic glycosides from Hedyotis scandens.
WGC Wang GuoCai, LT Li Tao, DFY Deng FangYe… - 2013 - cabidigitallibrary.org
Five new phenolic glycosides, hedyotosides AE (1-5), including a new cyanogenic glycoside
(1), along with 10 known compounds (6-15) were isolated from the whole plants of Hedyotis
scandens. The structures of compounds 1-5 were established by extensive spectroscopic
analyses and acid hydrolysis. All the isolated compounds were evaluated for their in vitro
antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect (CPE)
reduction assay. Compounds 6 and 15 showed anti-RSV effects with IC50 values of 20 and …
(1), along with 10 known compounds (6-15) were isolated from the whole plants of Hedyotis
scandens. The structures of compounds 1-5 were established by extensive spectroscopic
analyses and acid hydrolysis. All the isolated compounds were evaluated for their in vitro
antiviral activity against respiratory syncytial virus (RSV) with cytopathic effect (CPE)
reduction assay. Compounds 6 and 15 showed anti-RSV effects with IC50 values of 20 and …
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