Gender differences in the renal response to renin-angiotensin system blockade

JA Miller, DZ Cherney, JA Duncan, V Lai… - Journal of the …, 2006 - journals.lww.com
Evidence suggests that gender differences exist in renin-angiotensin system (RAS) function.
It was hypothesized that women may differ also in their response to RAS blockade. The
renal and peripheral hemodynamic responses to incremental dosages of an angiotensin
receptor blocker and the degree of angiotensin II (AngII) insensitivity achieved during 8 wk
were examined in men and women. Participants were 30 young healthy men (n= 15; mean
age 27±2) and women (n= 15; mean age 28±2) who were on a controlled sodium and …
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