Identification of novel breast cancer susceptibility and resistance genes in genetically
diverse human populations is challenging, and so inbred rats have been used to identify
novel mammary cancer susceptibility quantitative trait loci (QTLs) with conventional mapping
approaches. An alternative approach for QTL mapping is to use chromosome substitution
(consomic) rat strains, which has the advantage of rapid generation of congenic from
consomic animals. Using a novel rat strain pair, SS and BN, we identified rat mammary …