… of these two processes, inhibition of either glycogenolysis or … of smallmolecule inhibitors of
glycogen phosphorylase (GP), … agent that inhibits both glycogen phosphorylase and CYP51 …

… and recent advances in new inhibitors of this structurally and … physiological consequences
of inhibiting glucose production … and promise in glycogen phosphorylase inhibitors (GPIs) as …

… Cholic acid/7-aza-indole derivatives incorporating diazobenzene spacer arms and their
glycogen phosphorylase inhibition towards rabbit muscle glycogen phosphorylase a (RMGPa). …

Introduction: Glycogen phosphorylase (GP) is the enzyme responsible for the synthesis of
glucose-1-phosphate, the source of energy for muscles and the rest of the body. The binding …

… inhibition aimed at attenuating hyperglycaemia is unlikely … a glycogen phosphorylase inhibitor
might favour glycogen recovery after exercise by activating glycogen synthase in glycogen …

… for providing the glycogen phosphorylase inhibitors used in our studies. Our research on
the physiological regulation of glycogen phosphorylase has been funded by Diabetes UK. …

… is cycled through the glycogen storage before efflux from the liver. This makes inhibition of
the … ) as a potent liver glycogen phosphorylase (GP) inhibitor, we have tested several other …

… catalyzes the first step in the phosphorolysis of glycogen, it has … glycogen phosphorylase,
and describes progress in our understanding of the mechanism of action of these inhibitors …

… , an inhibitor of human liver glycogen phosphorylase is reported that functionally inhibits
GGN-… that glycogen phosphorylase inhibitors may be useful in the treatment of type 2 diabetes. …

… In the context of this survey, the biological space is represented by glycogen
phosphorylase (GP), the main regulatory enzyme of glycogen metabolism. GP, catalysing …